Bed bugs. Few words strike such fear in the minds of travelers. In cities around the world, lurking beneath the plush blankets of otherwise pristine-looking hotel beds are tiny bloodthirsty beasts just waiting for weary wanderers to surrender to a vulnerable slumber. Though bed bugs today have infested the globe, the common bed bug is not a new pest at all. Indeed, as Brooke Borel reveals in this unusual history, this most-reviled species may date back 250,000 years, wreaking havoc on our collective psyche while even inspiring art, literature, and music—in addition to vexatious red welts.